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Sleep Disorder
Drugs
According to the National Sleep
Foundation, one out of every four Americans take some form of
sleep-aid medication or sedative to help them sleep better or
longer. Insomnia, the most common type of sleeping disorder,
affects an estimated 60 million Americans each year, with
sufferers experiencing an inability to fall asleep, stay
asleep, or feel refreshed after waking. Studies have linked a
lack of sleep to many chronic diseases and conditions,
including diabetes, cardiovascular diseases, obesity, and
depression.
Prescription and over-the-counter
medications are the most commonly prescribed treatment option
for people suffering from insomnia or other sleep disorders,
especially if the conditions are chronic or occur frequently.
Medications such as sedatives and hypnotics allow patients to
fall asleep and stay asleep longer by acting on certain
chemicals in the brain. These chemicals are often unbalanced in
people suffering from insomnia. By getting more high-quality
sleep, daily mental and physical functioning is often
dramatically improved in patients taking sleep medications.
Common drugs used in the treatment of sleep disorders
include:
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Antihistamines (Nytol,
Sleep-Eez, Sominex, Benadryl, Advil PM, Excedrin
PM, Tylenol PM, Unisom)
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Barbiturates (Luminal,
Mebaral)
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Benzodiazepine hypnotics
(Valium, Klonopin, Halcion, Ativan, Xanax, Serax, ProSom)
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Non-benzodiazepine
hypnotics (Sonata, Lunesta, Ambien)
Side Effects
To avoid unwanted side effects, sleep medications are
typically prescribed for short-term periods (two weeks or
less). Some strong hypnotics such as Lunesta can cause
withdrawal symptoms when treatment is stopped, with symptoms
including anxiety, sweating, vomiting, nausea, and shakiness.
Most prescription sleep medications can cause side effects such
as next-day drowsiness, dizziness, facial swelling, headache,
bloating, constipation, blurred vision, dry mouth, nausea, or
strange sleep-behaviors.
Interactions and
Warnings
Hypnotics or other sleep-aids
should not be combined with other medications that cause
drowsiness, such as prescription pain medications,
over-the-counter cough and cold medications, drugs for
depression or other psychiatric disorders, or drugs for
treating Parkinson’s disease. Sleep disorder drugs should never
be used with alcohol, as a patient’s heart rate could be slowed
to dangerous or even deadly levels. Certain drugs such as oral
contraceptives or activities such as smoking may also affect
the absorption of sleep medications in the body, causing
adverse effects or dangerously slowed breathing.
FDA Warnings on Sleep
Drugs
The U.S. Food and Drug
Administration (FDA) strengthened warning labels on all
sedative-hypnotic sleep medications to warn of the potential
for the drugs to cause severe allergic reactions and dangerous
sleep-related behaviors, such as sleep-driving, accompanied by
amnesia. Drugs with the heightened warning labels include
Ambien, Ambien CR, Dalmane, Doral, Halcion, Lunesta, ProSom,
Restoril, Rozerem, Sonata, and others. Sleep aids have been
shown to cause strange sleep behaviors in rare cases, such as
driving while asleep, cooking food while asleep, or wandering
at night, with little memory of the event the following
day.
Sources:
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http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm101557.htm
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http://www.fda.gov/ForConsumers/ByAudience/ForWomen/ucm118563.htm
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http://www.mayoclinic.com/health/insomnia/DS00187
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http://www.mayoclinic.com/health/insomnia/DS00187/DSECTION=treatments-and-drugs
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http://www.mayoclinic.com/health/sleeping-pills/SL00010
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http://www.mayoclinic.com/health/melatonin-side-effects/AN01717
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http://www.mayoclinic.com/health/sleep-aids/AN01820
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http://www.mayoclinic.com/health/sleep-aids/SL00016
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http://www.nlm.nih.gov/medlineplus/sleepdisorders.html
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http://www.sleepfoundation.org/article/sleep-america-polls/2002-adult-sleep-habits
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